DNA Isolation

Automation

SelectNA™plus

 SelectNAplus Instrument Benefits:
  • Innovative walk-away pathogen DNA extraction
  • Human-DNA-removal technology (MolYsis™)
  • Validated for primary sterile body fluids and tissues
  • DNA-free consumables and reagents
  • Bench-top instrument
  • Flexible:  1 to 12 samples
  • Superior diagnostic performance
  • Suitable for Next Generation Sequencing

The complete solution for broad-range pathogen diagnosis

Molzym’s MolYsis™ technology is an approach for selective lysis of human cells and degradation of released human DNA followed by isolation of purified microbial DNA. In a long list of publications, MolYsis™ has been documented to be a powerful tool of providing minute amounts of microbial DNA from a wide variety of clinical material to ultra-sensitive molecular testing.  

Now, Molzym for the first time has developed a fully automated, walk-away system, SelectNA™plus, that proceeds clinical material through the MolYsis™ method. The kit MolYsis-SelectNA™plus allows the extraction of DNA from enriched microbes from whole blood and other body fluids, tissues and swabs. For the automatic extraction and Real-Time PCR diagnosis of pathogen DNA a kit, Micro-Dx™, is provided.

SelectNA™plus is the instrumental component of the complete system, Micro-Dx™. The instrument is used for the fully automated extraction and purification of pathogen DNA from whole blood and other primary body fluids, swabs and tissue samples based on the MolYsis™ technology. SelectNA™plus considerably saves hands-on time in the most laborious part, DNA isolation, and at the same time decreases errors by handling. The highly contained automat avoids air-borne and cross contamination during pre-analysis and thus reduces false-positive results in PCR or Real-Time PCR analyses.

 

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Kit - MTB-DNA Blood

Blutbahn Homepage Benefits:
  • Extraction of highly enriched MTB DNA from whole blood and other sterile body fluids
  • Up to 10ml sample volume
  • Validated in clinical studies
  • Extraction of MTB DNA from live cells only
  • Reagents and consumables included
  • Enhances the diagnostic sensitivity in Real-Time PCR assaying
 
MTB-DNA Blood is based on Molzym’s MolYsis™ technology which removes non-target human DNA and enriches Mycobacterium tuberculosis  from blood and other liquid specimens. This pathogen can be present in samples at only very low loads. The optimised protocol therefore offers the possibility of extracting large sample volumes. Eventually, the enrichment of MTB DNA increases the diagnostic sensitivity of MTB-directed Real-Time PCR assays (tested: Fluorotype® MTB, Hain Lifescience, Germany; GeneXpert® MTB/RIF, Cepheid, Germany).

Order information:

Kit
Application
Content
Order no.
Contact
MTB-DNA Blood

Whole blood +

Body Fluids 

25 reactions
G-300-025 
Tel.: +49(0) 421 69 61 62-0
Fax: +49(0) 421 69 61 62-11
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
50 reactions
G-300-050 

 

MTB-DNABlood Kit Content (25 or 50 reactions)
  • Isolation of enriched MTB-DNA
  • Removal of irrelevant human and “dead” microbial DNA
  • DNA-free reagents and plastics
  • Small and large volumes: 1 to 10ml samples

 

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Technology - Automation

- under construction -

 

Kit - Automation

The SelectNA™ Blood Pathogen Kit combines the manual procedure for host DNA removal and pathogen enrichment from blood samples with the automated extraction and purification of pathogen DNA. The DNA is highly pure and can be used for direct PCR testing. The kit further contains DNA-free plastic consumables necessary for the automated protocol.

  Kit   Description  Size
  Quotation Request  
SelectNA™ Blood Pathogen Kit  Blood sample pre-treatment and pathogen DNA isolation  48 request

 

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